Next seminar : Séminaire du LPTMS : Olivier Martin (IPS2)

Tuesday, September 27 2022 at 11:00:00

Minimum complexity drives regulatory logic in Boolean models of living systems

Olivier Martin (Institut for Plant Sciences Paris Saclay)

Hybrid: onsite seminar + zoom. Register for this meeting: https://cnrs.zoom.us/meeting/register/tJIqde6gpjsoHNRUFnSHp__QPqHYPzkNQd8N After registering, you will receive a confirmation email containing information about joining the meeting. We study the preponderance of particular types of Boolean functions in gene regulatory networks. We first compile a reference dataset of 2687 functions extracted from published models. This dataset shows strong enrichments in "read-once" functions and in nested canalyzing functions. These enrichments can be justified by selection for minimum complexity, either Boolean complexity based on string lengths in formal logic which is yet unexplored in the biological context, or average sensitivity which corresponds to maximizing robustness to noise.

Last Highlight : The Journal of Physics A 2022 awards

The Journal of Physics A: Mathematical and Theoretical announced its 2022 awards.

The Early Career Researcher Best Paper Prize is awarded to Valentina Ros.

More details: https://iopscience.iop.org/journal/1751-8121/page/Best%20Paper%20Prize


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