Physics-Biology interface seminar

Held every second Wednesday at 11am in the moyen amphi at LPS (not LPTMS!) in Orsay, this seminar series aims to be a central forum for the Physics/Biology interface in the south of Paris.

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Other seminars and conferences you might be interested in:

Paris-Saclay Biomechanics seminar - last Thu. of the month in Palaiseau (subscribe to their announcements)
Seminar of the Physical Chemistry Laboratory - in Orsay

Informations for speakers
Past seminars
Contact the organizer


Nanodiamond based quantum sensors for biological applications

Quan Li (Chinese University of Hong Kong, China)

Special location: Laboratoire Aimé Cotton, Orsay

Nanodiamond (ND) with Nitrogen-vacancy (NV) centers serves as promising bio-sensor due to its excellent bio-compatibility, high photo-stability, and the long spin coherence time at room temperature. However, the complicated biological environment, e.g. in a single cell, imposes stringent requirements on the sensor probes to be internalized. In this talk, I will discuss the requirements on nanodiamond as intra-cellular sensor, and the possible strategies that will enable various bio-sensing measurements. I will start with the understanding of nanodiamond-cell interfaces, from anchoring of ND on the plasma membrane to their internalization, and eventually to their intracellular trafficking. Other than the conventional three-dimensional trajectories tracking of the ND, it is also possible to track their orientations (rotation), providing additional information of the intracellular environment. One problem with NV based bio-sensing is that the NV center is less sensitive to certain parameters such as temperature and pressure, and not at all response to many other important biochemical parameters such as pH and non-magnetic biomolecules. I will also discuss possible schemes of constructing nanodiamond based hybrid sensors, which lead to significantly enhanced sensitivity and/or potentially enable the measurement of various biochemical parameters using NV based quantum sensing.

Location:

David Bensimon (LPS-ENS, Paris, France)

Location: Moyen Amphi, Building 510, Université Paris-Sud Orsay

Karim Benzerara (IMPMC, Université Pierre et Marie Curie)

Location: Moyen Amphi, Building 510, Université Paris-Sud Orsay

Bacterial collective behaviours

Knut Drescher (Max Planck Institute for Terrestrial Microbiology, Marburg, Germany

In nature, bacteria often engage in a range of collective behaviors. In this presentation, I will demonstrate how two bacterial behaviors, swarming and biofilm formation, are related by physical interactions, chemical signaling, and dynamical transitions. I will show how these collective behaviors arise from cell-cell interactions, and the physiological state of individual cells. Furthermore, I will introduce new experimental methods for investigating bacterial collective behaviors.

Location: Moyen Amphi, Building 510, Université Paris-Sud Orsay